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Alex Ryan's avatar

Any conversation of Alzheimer’s should involve Dale Bredesen.

He’s the guy who actually SOLVED the problem.

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Robin Whittle's avatar

Anyone who really wants to reduce Alzheimer's disease, Parkinson's disease, Multiple System Atrophy, dementia with Lewy bodies and other forms of dementia would sooner or later think of nutrition and vitamin D and do a quick Google Scholar search on "vitamin D" and "dementia", "Alzheimer's disease" or whatever.

Here https://vitamindstopscovid.info/00-evi/#3.3 are a few of the many articles they would find, which show that most, and perhaps all forms of age-related neurodegeneration generally only occur in people with even lower 25-hydroxyvitamin D levels than the lousy levels of the general population, who have only 1/4 to 1/2 of the 50 ng/mL 125 nmol/L circulating 25-hydroxyvitamin D their immune system needs to function properly, including reducing the risk of excessive inflammatory responses.

I have not yet updated the section https://vitamindstopscovid.info/00-evi/#sjw-updated-ratios on how much vitamin D to take to accord with Prof. Wimalawansa's recently simplified ranges of ratios, which he presented in a recent FLCCC webinar 56:26 at: https://covid19criticalcare.com/understanding-vitamin-d/ . This is a simplification of the ranges of ratios he recommended in: "Rapidly Increasing Serum 25(OH)D Boosts the Immune System, against Infections - Sepsis and COVID-19" Nutrients 2022-07-21: https://www.mdpi.com/2072-6643/14/14/2997.

His recommended vitamin D3 daily average supplemental intake quantities, as ranges of ratios of body weight:

70 to 90 IU / kg BW for those not suffering from obesity (BMI < 30).

100 to 130 IU / kg BW for obesity I & II (BMI 30 to 39).

140 to 180 IU / kg BW for obesity III (BMI > 39).

For 70 kg 154 lb without obesity, 0.125 mg (5000 IU) a day is a good amount. This is a gram every 22 years, and pharma-grade vitamin D3 costs about USD$2.50 a gram ex-factory. Higher ratios of body weight are required for those suffering from obesity, since this reduces the ability of the liver to hydroxylate vitamin D3 to 25-hydroxyvitamin D and because excess adipose tissue tends to absorb both vitamin D3 and 25-hydroxyvitamin D: https://vitamindstopscovid.info/00-evi/#obesity-deficit .

If everyone followed Prof. Wimalawansa's recommendation, almost everyone's 25-hydroxyvitamin D would be at least the 50 ng/mL 125 nmol/L their immune system needs to function properly. With no vitamin D3 supplementation, and no recent summertime UV-B skin exposure, most people have only 1/10 to 1/2 of the 25-hydroxyvitamin D they need to be healthy. Government recommended vitamin D3 daily supplemental intake quantities, such as 0.02 mg (800 IU), help somewhat, but are a fraction of what people need for proper immune system function.

If everyone did this, there would be no pandemic influenza or COVID-19 - and sepsis (11 million deaths worldwide in 2017, https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)32989-7/) would be rare. Likewise dementia, Kawasaki disease and MIS-C.

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